Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-12-16
1999-12-28
Allen, Marianne P.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 6, 4353201, 435325, 536 235, C12N 1512
Patent
active
060080175
ABSTRACT:
HC/BTLP polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing hC/BTLP polypeptides and polynucleotides in the design of protocols for the treatment of restenosis, atherosclerosis, congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), benign prostatic hypertrophy (BPH), nephritis, fibrosis, glomerulonephritis, gliosis, cirrhosis and anomalies of wound healing, such as keloids among others, and diagnostic assays for such conditions.
REFERENCES:
GenBank Accession No. U34042.
Takahara, et al., "Characterization of a Novel Gene Product (Mammalian Tolloid-like) with High Sequence Similarity to Mammalian Tolloid/Bone Morphogenetic Protein-1", Genomics 34:157-165(1996).
Human Genome Sciences, Corporation EST #837970.
Takahara et al UBC 269 (51) 32572-32578 (1994).
GenBank Q62381; GenBank MMV 34042.
George et al "Current Methods in Sequence Comparison and Analysis" in Macromolecular Sequencing and Synthesis pp. 127-149, edited by David H. Schlesinger, Alan R. Liss, Inc NY (1988).
Arleth Anthony J
Elshourbagy Nabil A.
Li Xiaotong
Willette Robert N
Allen Marianne P.
Han William T.
King William T.
SmithKline Beecham Corporation
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