Human capsaicin receptor and uses thereof

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C436S501000

Reexamination Certificate

active

06867009

ABSTRACT:
This invention provides novel human capsaicin receptors and the nucleotide sequences encoding these receptors. Also provided are vectors encoding these receptors and mammalian and non-mammalian cells expressing these vectors. Further provided are assays for identifying compounds that modulate capsaicin receptors and diagnostic assays for capsaicin receptor polymorphisms and aberrant capsaicin receptor expression.

REFERENCES:
patent: 6239267 (2001-05-01), Duckworth et al.
patent: 6335180 (2002-01-01), Julius et al.
patent: 6406908 (2002-06-01), McIntyre et al.
patent: 20030003536 (2003-01-01), McIntyre et al.
patent: WO 9909140 (1999-02-01), None
patent: WO 9937675 (1999-07-01), None
patent: WO 0029577 (2000-05-01), None
patent: WO 0032766 (2000-06-01), None
patent: WO 0063415 (2000-10-01), None
Acs et al. Trifluorperazine Modulates [3H]Resiniferatoxin Binding by Human and Rat Vanilloid (Capsaicin) Receptors and Affects 45Ca Uptake by Adult Rat Dorsal Root Ganglion Neurones. Sep. 1, 1995, Pharmacol. and Experim. Therapeutics. 274(3):1090-8.*
Caterina et al., “The Capsaicin Receptor: a heat activated ion channel in the pain pathway,” Nature 389:816-824 (1997).
Caterina et al., “A capsaicin-receptor homologue with a high threshold for noxious heat,” Nature 398:436-441 (1999).
Szallasi et al., “The Cloned Rat Vanilloid Receptor VR1 Mediates Both R-Type Binding and C-Type Calcium Response in Dorsal Root Ganglion Neurons,” Molecular Pharmacology 56:581-587 (1999).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Human capsaicin receptor and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human capsaicin receptor and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human capsaicin receptor and uses thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3392480

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.