Human calcium-binding phosphoprotein

Details Human calcium-binding phosphoprotein Human calcium-binding phosphoprotein

1998-06-11

1999-07-27

Hendricks, Keith D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, 530350, A61K 3817, C07K 14435

Patent

active

059290293

ABSTRACT:
The invention provides a human calcium-binding phosphoprotein (CBPP-1) and polynucleotides which identify and encode CBPP-1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of CBPP-1.

REFERENCES:
patent: 5498533 (1996-03-01), Poovaiah et al.
Celio, M.R., et al., "Introduction to EF-hand calcium-binding proteins," Guidebook to Calcium,-binding Proteins, Oxford University Press, Oxford, UK, pp. 15-20 (1996).
Lefort, A., et al., "Cloning and sequencing of a calcium-binding protein regulated by cyclic AMP in the thyroid," The EMBO Journal, 8(1):111-116 (1989) (GI 876; 877).
Nemoto, Y., et al., "R2D5 Antigen: a Calcium-binding Phosphoprotein Predominantly Expressed in Olfactory Receptor Neurons," The Journal of Cell Biology, 123(4):963-976 (1993).
Mulkey, R.M., et al., "An Essential Role for Protein Phosphatases in Hippocampal Long-Term Depression," Science, 261:1051-1055 (1993).
El Housini, H., (GI 1359716 and GI 1359717) GenBank Sequence Database (Accession X97966), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894.

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