Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1997-10-01
2000-09-26
Chan, Christina Y.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
436544, 530327, 530839, 530841, C07K 1447
Patent
active
061244309
ABSTRACT:
The present invention provides reagents and assays for the quantification of hBNP in biological fluid samples such as plasma or serum. Antibodies are provided which are monospecific to epitopes comprising the amino acid sequences 5-13, 1-10 and 15-25 of hBNP. These antibodies, and peptide fragments containing these sequences, can be employed in the assays of the invention, which may be carried out in a sandwich format or a competition format.
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Lim Garrett A.
Mischak Ronald P.
Scardina Jan Marian
Chan Christina Y.
Gambel Phillip
Scios Inc.
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