Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1998-05-01
2000-06-27
Hutzell, Paula K.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 231, C07H 2104, C07H 2102
Patent
active
060808489
ABSTRACT:
The invention provides a human human brain-associated protein (HBAP-1) and polynucleotides which identify and encode HBAP-1. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HBAP-1.
REFERENCES:
Liu, F. et al., GenBank Sequence Database, (Accession R28639), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894, Mar. 24, 1993.
McCance, K.L. and S.E. Huether, (1994) Pathophysiology The Biologic Basis for Disease in Adults and Children, 2nd Ed., Mosby-Yearbook, Inc., St. Louis, MO pp. 404-410.
Robbins, S.L. et al., (1994) Pathologic Basis of Disease, 5th Ed., W.B. Saunders Co., Philadelphia, PA pp. 1329-1335 and 1342-1346.
McCance, K.L. (supra), p. 504.
Coon, H. et al., "Genomic Scan for Genes Predisposing to Schizophrenia", Am. J. Med. Genet., 54:59-71 (1994).
Karayiorgou, M. et al., "Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11", Proc. Natl. Acad. Sci. USA, 92:7612-7616 (1995).
Yamada, Y. et al., "Human Somatostatin Receptor Genes: Localization to Human Chromosomes 14, 17, and 22 and Identification of Simple Tandem Repeat Polymorphisms", Genomics, 15:449-452 (1993).
Rohrer, L. et al., "Cloning and characterization of a fourth human somatostatin receptor", Proc. Natl. Acad. Sci. USA, 90:4196-4200 (1993).
Yamada, Y. et al., "Cloning and functional characterzation of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney", Proc. Natl., Acad. Sci. USA, 89:251-255 (1992).
Bito, H. et al., "Functional Coupling of SSTR4, a Major Hippocampal Somatostatin Receptor, to Adenylate Cyclase Inhibition, Arachidonate Release, and Activation of the Mitogen-activated Protein Kinase Cascade", J. Biol. Chem., 269:12722-12730 (1994) (GI 401131).
Bito, H. et al., (Direct Submission), GenBank Sequence Database (Accession 401131), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 401131).
Au-Young Janice
Baughn Mariah R.
Corley Neil C.
Guegler Karl J.
Henrichwark Sven
Hutzell Paula K.
Incyte Pharmaceuticals Inc.
Pasqualone Danielle M.
Worrall Timothy A.
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