Human body weight management

Details Human body weight management Human body weight management

1992-10-21

1997-07-01

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3144

Patent

active

056439288

ABSTRACT:
A therapeutic method and article of manufacture to manage human body weight with the use of cotinine or pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 3048520 (1962-08-01), McKennis et al.
patent: 3867519 (1975-02-01), Michaels
patent: 3870791 (1975-03-01), Haddad et al.
patent: 3870794 (1975-03-01), Hutchinson et al.
patent: 4051842 (1977-10-01), Hazel et al.
patent: 4136177 (1979-01-01), Lin et al.
patent: 4140122 (1979-02-01), Kuhl et al.
patent: 4255415 (1981-03-01), Chrai et al.
patent: 4383529 (1983-05-01), Webster
patent: 4621074 (1986-11-01), Bourne
patent: 4668506 (1987-05-01), Bawa
patent: 4713244 (1987-12-01), Bawa et al.
patent: 4788063 (1988-11-01), Fisher et al.
patent: 4931279 (1990-06-01), Bawa et al.
patent: 4946853 (1990-08-01), Bannon et al.
patent: 5298257 (1994-03-01), Bannon et al.
Cynthia S. Pomerleau et al., "The Female Weight-Control Smoker: A Profile", J. Substance Abuse, 5, 391, (1993).
Raymond Niaura et al., "Increased Saliva Cotinine Concentrations in Smokers During Rapid Weight Loss," J. Consult. Clin. Psychol., 60, 985, (1992).
Ovide F. Pomerleau et al., "Effects of Fluoxetine on Weight Gain and Food Intake in Smokers Who Reduce Nicotine Intake," Psychoneuroendocrinology, 16, 433 (1991).
M. E. Carroll et al., "Nicotine Dependence in Rats," Life Sciences, 45, 1381-1388 (1989).
W. G. Frankenberg et al., "The chemistry of tobacco fermentation. I. Conversion of the alkaloids. D. Identification of cotinine in fermented leaves," J. Am. Chem. Soc., 79, 149-151 (1957).
E. J. LaVoie et al., "Evaluation of the effects of cotinine and nicotine-N'-oxides in the development of tumors in rats initiated with N-[4-(5-nitro-2-furyl)-2-thiazoyl]formamide," J. Nat. Cancer Institute, 75, 1075-1081 (1985).
R. C. O'Neill, "Tobacco products containing nicotine antagonists," Chemical Abstracts, 55, 16920 (1961).
M. Rosa et al., "How the steady-state cotinine concentration in cigarette smokers is directly related to nicotine intake," Clin. Pharmacol. Ther., 52, 324-329 (Sep. 1992).
R. Barbieri et al, "Nicotine, Cotinine and Anabasine Inhibit Aromatase in Human Trophoblast in Vitro", J. Clin. J. Steroid Invest., 77:1727-1733 (1986).
R. Barbieri et al, "Nicotine, Cotinine and Anabasine on Rat Adrenal 11B-hydroxylase and 21-hydroxylase", J. Steroid Biochem., 28: 25-28 (1987).
R. Barbieri, et al, "Cotinine and Nicotine Inhibit Human Fetal Adrenal 11B-hydroxylase", Journal of Clinical Endocrinology and Metabolism, 69:1221-1224 (1989).
N. Benowitz et al, "Cotinine Disposition and Effects", Clin. Pharmacol. Ther., 34:604-611 (1983).
N. Benowitz et al, "Inverse Relation Between Serum Cotinine Concentration and Blood Pressure in Cigarette Smokers", Circulation, 80:1309-1312 (1989).
J. Borzelleca et al, "Studies on the Respiratory and Cardiovascular Effects of (-)-Cotinine", J. Pharm. Exper. Therapeutics, 137:313-318 (1962).
K. Bauman et al, "Validity of Self-Reports of Smokeless Tobacco Use and Validity of Cotinine as an Indicator of Cigarette Smoking", The American Journal of Epidemiology, 130:327-337 (1989).
E. Bowman et al, "(-)-Cotinine", Biochemical Preparations, 10:36-39 (1963).
E. Bowman et al, "Disposition and Fate of (-)-Cotinine in the Mouse", The Journal of Pharmacology and Experimental Therapeutics, 143:301-308 (1963).
E. Bowman et al, "Studies on the Metabolism of (-)-Cotinine in the Human", J. Pharmacol. Exp. Ther., 135:306-311 (1962).
R. Chahine et al, "The in Vitro Effects of Nicotine and Cotinine on Prostacyclin and Thromboxane Biosynthesis", Prostaglandins, Leukotrienes, and Essential Fatty Acids, 40:261-266 (1990).
M. Curvall et al, "Simulation and Evaluation of Nicotine Intake During Passive Smoking: Cotinine Measurements in Body Fluids of Nonsmokers Given Intravenous Infusions of Nicotine", Clinical Pharmacol Therapy, 47:42-49 (1990).
M. Curvall et al, "The Pharmacokinetics of Cotinine in Plasma and Saliva from Non-Smoking Healthy Volunteers", The European Journal of Clinical Pharmacology, 38:281-287 (1990).
E. Di Giusto et al, "Some Properties of Saliva Cotinine Measurements in Indicating Exposure to Tobacco Smoking", The American Journal of Public Health, 76:1245-1246 (1986).
P. DeSchepper et al, "Kinetics of Cotinine After Oral and Intravenous Administration to Man", The European Journal of Clinical Pharmacology, 31:583-588 (1987).
J. Gabrielsson et al, "Constant-Rate Infusion of Nicotine and Cotinine. I. A Physiological Pharmacokinetic Analysis of the Cotinine Disposition, and Effects on Clearance and Distribution in the Rat", The Journal of Pharmacokinetics and Biopharmaceutics 15:583-599 (1987).
R. Galeazzi et al, "Steady-Stroke Concentration of Cotinine as a Measure of Nicotine-Intake by Smokers", The European Journal of Clinical Pharmcology, 28:301-304 (1985).
D. Glenn et al, "Synthesis and Mass Spectrometry of Some Structurally Related Nicotinoids", The Journal of Organic Chemistry, 43:2860-2870 (1978).
S. Goldberg et al, "Nicotine and Some Related Compounds: Effects on Schedule-Controlled Behavior and Discriminative Properties in Rats", Psychopharmacology, 97:295-302 (1989).
N. Heimstra, "The Effects of Smoking on Mood Change". (1986).
R. Hutchinson et al, "Effects of Nicotine on Avoidance, Conditioned Suppression and Aggression Response Measures in Animals and Man", 171-196. (1989).
J. Idle, "Titrating Exposure to Tobacco Smoke Using Cotinine-A Minefield of Misunderstanding", The Journal of Clinical Epidemiol, 43:313-317 (1990).
P. Jacob et al, "Disposition Kinetics of Nicotine and Cotinine Enantiomers in Rabbis and Beagle Dogs", The Journal of Pharmaceutical Sciences, 77:396-400 (1988).
L. Jarczyk et al, "Serum and Saliva Concentrations of Cotinine in Smokers and Passive Smokers", The Journal of Clinical Chemical Biochemistry, 27:230-231 (1989).
M. Jarvis et al, "Biochemical Markers of Smoke Absorption and Self Reported Exposure to Passive Smoking", The Journal of Epidemiology and Community Health, 38:335-339 (1984).
J. Jordanov, "Cotinine Concentrations in Amniotic Fluid and Urine of Smoking, Passive Smoking and Non-Smoking Pregnant Women at Term and in the Urine of Their Neonates on 1st Dat of Life", The European Journal of Pediatrics, 149:734-737 (1990).
K. Kim et al, "Effects of Some Nicotine Metabolites and Related Compounds on Isolated Smooth Muscle", The Journal of Pharmacology and Experimental Therapeutics, 161:59-69 (1968).
B. Kuo et al, "Influence of Nicotine and Cotinine on the Expression of Plasminogen Activator Activity in Bovine Aortic Endothelial Cells", Thrombosis and Haemostasis, 61:70-76 (1989).
G. Kyerematen et al, "Disposition of Nicotine and Eight Metabolites in Smokers and Nonsmokers: Identification in Smokers of Two Metabolites That are Longer Lived Than Nicotine", Clinical Pharmacol Ther., 48:641-651 (1990).
W. Luck et al, "Extent of Nicotine and Cotinine Transfer to the Human Fetus, Placenta and Amniotic Fluid of Smoking Mothers", Dev. Pharmacol. Ther., 8:384-395 (1985).
C. Lynch et al, "Spontaneous Cigarette Brand Switching: Consequences for Nicotine and Carbon Monoxide Exposure", The American Journal of Public Health, 78:1191-1194 (1987).
H. McKennis et al, "Demethylation of Cotinine in Vivo", Demethylation of Cotinine in Vivo, 81:3951-3954 (1959).
H. McKennis et al, "Alternate Routes in the Metabolic Degradation of the Pyrrolidine Ring of Nicotine", The Journal of Biological Chemistry, 239:3990-3996 (1964).
A. Meikle et al, "Nicotine and Cotinine Effects on 3 Alpha Hydroxysteroid Dehydrogenase in Canine Prostate", Life Sciences, 43:1845-1850 (1988).
A. McNeill et al, "Saliva Cotinine as an Indicator of Cigarette Smoking in Adolescents", The British Journal of Addiction, 82:1355-1360 (1987).
M. Noland et al, "Saliva Cotinine and Thiocyanate: Chemical Indicators of Smokeless Tobacco and Cigarette Use in Adolescents", The Journal of Behavioral Medicine, 11:423-433 (1988).
M. Risner et al, "Effects of Nicotine, Cocaine and Some of Thier Metabolites on Schedule-Controlled Responding by Beagle Dogs and Squirrel Monkeys", The Journal of Pharmacology and Experimental Therapeutics, 234:113-119 (1985).
Rylander et

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