Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1995-06-07
1998-11-03
Eisenschenk, Frank C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303879, 5303881, 53038822, 5303887, 5303896, 435331, 435334, 435346, C07K 1628, C12P 2108
Patent
active
058310290
ABSTRACT:
DNA encoding a novel human .beta..sub.2 integrin .alpha. subunit polypeptide, designated .alpha..sub.d, is disclosed along with methods and materials for production of the same by recombinant procedures. Fusion proteins are also disclosed which include extracellular .alpha..sub.d protein fragments, .alpha..sub.d I domain fragments or full length .alpha..sub.d polypeptides and human immunoglobulin constant regions. Binding molecules specific for .alpha..sub.d are also disclosed as useful for modulating the biological activities of .alpha..sub.d. DNA from other species which show homology to human .alpha..sub.d encoding sequences are also disclosed.
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Gallatin W. Michael
Van der Vieren Monica
Eisenschenk Frank C.
ICOS Corporation
Rabin Evelyn
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