Human B-cell differentiation factor and process of producing sai

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4352523, 435 691, 4351723, 4352402, 4353201, 4352351, 4352542, 536 235, 536 2351, 530350, 935 9, 935 18, 935 27, 935 32, 935 41, 935 56, 935 70, C12P 2102, C12P 1934, C12N 1500, C12N 500, C12N 700, C12N 121, C12N 116, C12N 118, C07K 300, C07H 1512

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053246403

ABSTRACT:
A cDNA and a chromosomal DNA coding for the human B-cell differentiation factor were provided and the entire nucleotide sequence of said DNAs as well as the entire amino acid sequences of the polypeptide portion of mature human B-cell differentiation factor and the leader peptide were revealed. The method for producing human B-cell differentiation factor by a recombinant gene technology was also provided.

REFERENCES:
Tsujimoto et al. "Purificaton and Characterizaton of Recombinant Human Interleukin 5 Expressed in Chinese Hamster Ovary Cells". J. Biochem., 106, pp. 23-28 (1989).
Nucleic Acids Research, vol. 14, No. 22, Nov. 22, 1988, pp. 9149-9158, Azuma: "Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue".
Proc. Natl. Acad. Sci. USA, vol. 84, Jun. 1987, pp. 4234-4238, Takatsu: "Interleukin 5 . . . ".
Chemical Abstracts, vol. 106, No. 21, May 1987, p. 152, No. 169856b, Kinashi: "Cloning of cDNA to T-cell replacing factor and identity with B-cell growth factor II".

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