Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1994-06-08
1996-06-25
Draper, Garnette D.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
424 851, 424 852, 530413, 530416, 530417, 435 6952, C07K 14715, C12P 2102, C12N 1524
Patent
active
055300987
ABSTRACT:
A cDNA and a chromosomal DNA coding for the human B-cell differentiation factor were provided and the entire nucleotide sequence of said DNAs as well as the entire amino acid sequences of the polypeptide portion of mature human B-cell differentiation factor and the leader peptide were revealed. The method for producing human B-cell differentiation factor by a recombinant gene technology was also provided.
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patent: 5324640 (1994-06-01), Honjo et al.
patent: 5362489 (1994-11-01), Kishimoto et al.
Azuma et al. (1986) Nucleic Acids Research 14:9149-9158.
Hirano et al. (1985) Proc. Natl. Acad. Sci. USA 82:5490-5494.
Takatsu et al. (1985) J. Immunol. 134:382-389.
Nucleic Acids Research, vol. 14, No. 22, Nov. 22, 1988, pp. 9149-9158, Azuma: "Cloning of cDNA for human T-cell replacing factor (interluekin-5) and comparison with the murine homologue".
Proc. Natl. Acad. Sci. USA, vol. 84, Jun. 1987, pp. 4234-4238, Takatsu: "Interleukin 5 . . . ".
Chemical Abstracts, vol. 106, No. 21, May 1987, p. 152, No. 169856b, Kinashi: "Clowning of cDNA to T-cell replacing factor and identity with B-cell growth factor II".
Tsujimoto et al. "Purification and Charcterization of Recombinant Human Interleukin 5 Expressed in Chinese Hamster Ovary Cells". J. Biochem., 106, pp. 23-28 (1989).
Honjo Tasuku
Severinson Eva
Takatsu Kiyoshi
Draper Garnette D.
Mertz Prema
Suntory Limited
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