Human ARL-related gene variants associated with cancers

Details Human ARL-related gene variants associated with cancers Human ARL-related gene variants associated with cancers

2006-08-08

2006-08-08

Siew, Jeff (Department: 1642)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100

Reexamination Certificate

active

07087733

ABSTRACT:
The invention relates to the nucleic acid sequences of two novel human ARL-related gene variants (ARLV1 and ARLV2) and the polypeptides encoded by ARLV1 and ARLV2.The invention also relates to the process for producing the polypeptides encoded by ARLV1 and ARLV2.The invention further relates to the use of the nucleic acid of ARLV1 and ARLV2 and the polypeptide encoded by ARLV1 and ARLV2 in diagnosing diseases associated with the deficiency of human ARLV gene, in particular large cell lung cancer or hepatocellular carcinoma.

REFERENCES:
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Andrew Chin, “On the preperation and utilization of isolated and purified oligonucleotides” [electronic resource], UNC Library, Mar. 14, 2002.
Deliang Cao, et al.; Identification and Characterization of a Novel Human Aldose Reductase-Like Gene, vol. 273, No. 19, Issue of May 8, pp. 11429-11435 1998.
“On the preparation and utilization of isolated and purified oligonucleotides” [electronic resource], Andrew Chin, allegedly deposited in UNC library on Mar. 14, 2002, date of publication, if any, is in question.
Cao et al., J. biol. Chem., 273: 11429-35 (1998).
Cao et al., Nucleotide Accession No. U37100.
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