Human apoptosis-associated genes and human...

Details Human apoptosis-associated genes and human... Human apoptosis-associated genes and human...

2008-01-08

2008-01-08

Yu, Misook (Department: 1642)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Reexamination Certificate

active

07317085

ABSTRACT:
As novel human apoptosis-related protein inducing apoptosis, a protein comprising the amino acid sequence of SEQ ID No. 2, 4 or 6 is provided. Moreover, a polynucleotide encoding the protein, an antibody against the protein, etc. are provided. These protein, polynucleotide and antibody are useful in, for example, diagnosis and treatment of cancers, autoimmune diseases, etc.

REFERENCES:
patent: 1074617 (2001-02-01), None
patent: WO99/40225 (1999-08-01), None
patent: 00/55175 (2000-09-01), None
patent: 01/53312 (2001-07-01), None
Ishiguro et al (Oncogene, Aug. 16, 2001, 20:5062-5066).
Tockman et al (Cancer Res., 1992, 52:2711s-2718s).
Gura (Science, 1997, 278:1041-1042.).
N. Akiyama et al., Identification of a Series of Transforming Growth Factor β-Responsive Genes by Retrovirus-Mediated Gene Trap Screening, Molecular and Cellular Biology, May 2000, vol. 20, No. 9, pp. 3266-3273.

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