Human antipneumococcal antibodies from non-human animals

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S388100, C530S388400, C435S007100

Reexamination Certificate

active

07078492

ABSTRACT:
The invention described herein provides human antibodies produced in non-human animals that specifically bind toStreptococcus pneumoniaecapsular polysaccharide (PPS-3). The invention further provides methods for making the antibodies in a non-human animal and for expressing the antibodies in cells including hybridomas and recombinant host cell systems. Kits and pharmaceutical compositions comprising the antibodies are also provided in addition to methods of treating, inhibitng or preventingS. pneumoniaeinfection or conditions or disorders caused by such infection by administering to a patient the pharmaceutical compositions described herein.

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