Human anti-NGF neutralizing antibodies as selective NGF...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S387300, C530S388100, C530S388150, C424S132100, C424S133100, C424S135100, C424S141100, C424S142100, C424S145100, C424S158100, C435S069600, C435S410000, C800S006000

Reexamination Certificate

active

07601818

ABSTRACT:
This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.

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