Human aminoacyl-tRNA synthetase polypeptides useful for the...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C512S002000, C435S068100

Reexamination Certificate

active

06903189

ABSTRACT:
The invention provides compositions comprising truncated tryptophanyl tRNA synthetase polypeptides useful for regulating angiogenesis, as well as nucleic acids encoding such truncated tRNA synthetase polypeptides. Methods of making and using such compositions are also disclosed.

REFERENCES:
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patent: WO 9913075 (1999-03-01), None
Tolstrup et al. (Jnl. Biol.Chem. vol. 270, No. 1 Jan. 1995, IDS).
Beresten et al. (European Jnl. Biochemistry, vol. 184, 1989, pp. 575-581).
Burgess et al., J of Cell Bio. 111:2129-2138, 1990.
Lazar et al. Molecular and Cellular Biology 8:1247-1252, 1988.
Fleckner et al. Proc.Natl.Acad.Sci. vol. 88, pp. 11520-11524, 1991.
Lemaire et al. Eur.J.Biochem. vol. 51. No. 1, pp. 237-252, 1975.

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