Human acid alpha glucosidase gene and bovine alpha-S1 casein...

Chemistry: molecular biology and microbiology – Vector – per se

Reexamination Certificate

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C435S004000, C435S006120, C435S069100, C435S183000, C435S195000, C435S206000, C435S252100, C536S023200, C536S024100

Reexamination Certificate

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06858425

ABSTRACT:
The invention provides polynucleotide sequences from the human acid alpha glucosidase gene and the bovine alpha S1 casein gene. These sequences are useful for designing transgenes for expression of human acid alpha glucosidase in the milk of transgenic animals. The sequences are also useful for design of primers and probes, and for computerized methods of sequence comparison.

REFERENCES:
patent: 5565334 (1996-10-01), Abe et al.
patent: WO9416057 (1994-07-01), None
Tzall et al. Identification of the promoter region and gene expression for human acid alpha glucosidase. Biochem. Biophys. Res. Comm., vol. 176(3):1509-1515, 1991.*
GenBank Accession No. X55079, Hoefsloot et al. dated Nov. 14, 1998.*
GenBank Accession No. X59856, Koczan et al. dated Oct. 24, 1991.*
GenBank Accession No. Q66990, Abe et al. dated Jul. 21, 1994.

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