Human 26S proteasome subunit components

Details Human 26S proteasome subunit components Human 26S proteasome subunit components

1995-07-24

1998-12-08

Prouty, Rebecca E.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435325, 4353201, 4351723, 435 691, 43525233, 536 232, 536 231, 536 235, C12N 121, C12N 1555, C12N 1512, C12N 1563

Patent

active

058468102

ABSTRACT:
Provided are P112 protein and P31 protein which proteins are among proteins constituting human 26S proteasome, DNAs encoding the proteins, vectors into which the DNAs are inserted and cells carrying the vectors.
The proteins of the present invention are useful not only for elucidating the function of the human 26S proteasome but also for the diagnosis or therapy of various diseases.

REFERENCES:
K. Kominami et al., "Nin 1p, a Regulatory Subunit of the 26S Proteasome is Necessary for Activation of Cdc28p Kinase of Saccharomyces cerevisiae", EBMO J. 14(13): 3105-3115, Jul. 1995.
GENBANK Locus NO. R16468, Apr. 1995.
GENBANK Locus No. R14974, Apr. 1995.
GENBANK Locus No. T87547, Mar. 1994.
GENBANK Locus No. T87548, Mar. 1995.
GENBANK Locus No. T10004, Apr. 1994.
GENBANK Locus No. R48899, May 1995.
GENBANK Locus No. R48792, May 1995.
Jikken Igaku, vol. 11, No. 20 (1993) 97-102.
Experimental Cell Research, 211 (1994) 203-211.
Experimental Cell Research, 200 (1992) 48-57.
Certificate of Application for Exemption of Application for Lack of Novelty (English translation).
J. Biol. Chem., vol. 269, No. 5 (1994) 3539-47.
J. Biol. Chem., vol. 269, No. 33 (1994) 20878-84.

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