Huchordin and uses thereof

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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536 235, 435 691, 4353201, 4352523, 530350, 514 12, C12N 1512, C12N 1563, C12N 510

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active

059899093

ABSTRACT:
The invention relates to huchordin polypeptides, nucleic acid molecules encoding huchordin, and uses thereof.

REFERENCES:
patent: 5679783 (1997-10-01), De Robertis et al.
patent: 5846770 (1998-12-01), LaVallie
Piccolo et al., "Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4" Cell 86:589-598, 1996.
Sasai et al., "Xenopus chordin: A Novel Dorsalizing Factor Activated by Organizer-Specific Homebox Genes" Cell 79:779-790, 1994.
Tolsma et al., "Peptides Derived from Two Separate Domains of the Matrix Protein Thrombospondin-1 Have Anti-Angiogenic Activity" J. of Cell. Biol. 122(2):497-511, 1993.
Volpert et al., "Inhibition of Angiogenesis by Thrombospondin-2" Biochem. & Biophys. Research Comm. 217(1):326-332, 1995.

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