HSV-1 vector containing a lat promoter

Details HSV-1 vector containing a lat promoter HSV-1 vector containing a lat promoter

1995-03-28

1998-12-15

Crouch, Deborah

Chemistry: molecular biology and microbiology

Vector, per se

4352351, 536 241, C12N 1500, C12N 700, C07H 2104

Patent

active

058495720

ABSTRACT:
A gene transfer vector for transferring genetic material to a host tissue and expressing a gene product therefrom includes a virus capable of establishing extra chromosomal viral latency in the host tissue. The strain includes at least one foreign gene recombined into the virus which is foreign to the viral genome and a promoter for initiating and driving transcription of the foreign gene during latency of the virus in the host tissue.

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