Hsp90 inhibitors, methods of making and uses therefor

Details Hsp90 inhibitors, methods of making and uses therefor Hsp90 inhibitors, methods of making and uses therefor

2005-08-31

2009-10-27

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S450000

Reexamination Certificate

active

07608611

ABSTRACT:
The invention provides purified 18,21-didehydro-18,21-dideoxo-18,21-dihydroxy-geldanamycin derivatives, pharmaceutically acceptable salts thereof and prodrugs thereof that are potent Hsp90 binding agents that are useful for the treatment and/or the amelioration of symptoms of cancer and other proliferative tissue disorders.

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