HSP90 inhibitors

Details HSP90 inhibitors HSP90 inhibitors

2009-01-30

2011-12-06

Olson, Eric S (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C514S264110

Reexamination Certificate

active

08071766

ABSTRACT:
The invention relates to HSP90 inhibiting compounds consisting of the formula:wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.

REFERENCES:
patent: 5654307 (1997-08-01), Bridges et al.
patent: 6534510 (2003-03-01), Barrow et al.
patent: 7345048 (2008-03-01), Ala et al.
patent: 7671059 (2010-03-01), Machajewski et al.
patent: 2004/0102458 (2004-05-01), Chiosis et al.
patent: 2005/0020534 (2005-01-01), Johnson et al.
patent: 2006/0079493 (2006-04-01), Fritz et al.
patent: 2007/0004674 (2007-01-01), Shiotsu et al.
patent: 2008/0160520 (2008-07-01), Amon et al.
patent: 0404355 (1990-12-01), None
patent: 1028405 (1966-05-01), None
patent: 1033384 (1966-06-01), None
patent: 2000038350 (2000-02-01), None
patent: WO99/61444 (1999-12-01), None
patent: WO/00/12497 (2000-03-01), None
patent: WO 01/70269 (2001-09-01), None
patent: WO02/09696 (2002-02-01), None
patent: WO02/15925 (2002-02-01), None
patent: WO02/36075 (2002-05-01), None
patent: WO02/069900 (2002-09-01), None
patent: WO02/094169 (2002-11-01), None
patent: WO/03/051844 (2003-06-01), None
patent: WO03/051844 (2003-06-01), None
patent: WO03/068776 (2003-08-01), None
patent: WO/03/097615 (2003-11-01), None
patent: WO2004/037978 (2004-05-01), None
patent: WO2004/081037 (2004-09-01), None
patent: WO2004/103274 (2004-12-01), None
patent: WO2005/028478 (2005-03-01), None
patent: WO2005/070929 (2005-08-01), None
patent: WO2005/080377 (2005-09-01), None
patent: WO2006/021448 (2006-03-01), None
patent: WO2006/050333 (2006-05-01), None
patent: WO2006/050457 (2006-05-01), None
patent: WO2006/052795 (2006-05-01), None
patent: WO2006/078891 (2006-07-01), None
patent: WO2006/083979 (2006-08-01), None
patent: WO2006/108107 (2006-10-01), None
patent: WO2006/113498 (2006-10-01), None
patent: WO2006/119504 (2006-11-01), None
patent: WO2006/124904 (2006-11-01), None
patent: WO2006/138265 (2006-12-01), None
patent: WO2007/035963 (2007-03-01), None
patent: WO2007/041362 (2007-04-01), None
patent: WO2007/082131 (2007-07-01), None
patent: WO2007/136603 (2007-11-01), None
patent: WO2007/139951 (2007-12-01), None
patent: WO2007/143630 (2007-12-01), None
patent: WO2007/147217 (2007-12-01), None
patent: WO2008/021981 (2008-02-01), None
patent: WO2008/045529 (2008-04-01), None
patent: WO2008/061208 (2008-05-01), None
patent: WO2008/063232 (2008-05-01), None
patent: WO2008/116216 (2008-09-01), None
patent: WO2008/142720 (2008-11-01), None
patent: WO/2008/154221 (2008-12-01), None
Ikuina et al. “Synthesis and Antitumor Activity of Novel O-Carbamoylmethyloxime Derivatives of Radicicoi” J. Med. Chem. 2003, 46, 2534-2541.
Barker et al. “Fragment-based Identification of HSP90 Inhibitors” ChemMedChem, 2009, vol. 4, p. 963-66.

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