Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1995-04-12
1998-09-15
Minnifield, N. M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530300, 530324, 530358, 4351723, C07K 1400, C07K 500, C07K 200, C12N 1500
Patent
active
058079939
ABSTRACT:
An autoantigen identified as HP-8 which is related to systemic lupus erythematosus. The HP-8 antigen is expressed by a gene which was identified by immunoscreening of human placental cDNA GT11 expression library with the monoclonal antibody 3E10. The 3E10 antibody is a low-affinity anti-double-stranded DNA autoantibody derived from the MRL murine models for human systemic lupus erythematosus.
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Alido Negemias T.
Chow Phoebe M.
French Cynthia K.
Yamamoto Karen K.
Minnifield N. M.
Reiter Stephen E.
VivoRx Autoimmune, Inc.
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