Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2011-03-29
2011-03-29
Rao, Manjunath N (Department: 1656)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S252330
Reexamination Certificate
active
07915011
ABSTRACT:
Disrupting the expression of endogenousEscherichiahost cell genes gcvA and spr provides mutant host cells having increased heterologous peptide production. The addition of a genetic modification to the coding region of gene yejM further enhances peptide production and facilitates easier downstream processing. RecombinantEscherichiahost cells are provided as well as methods of using such host cells for heterologous peptide production.
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Chen Qi
Cheng Qiong
Croker Kevin Michael
Friedmann Thomas Eduard
Ruebling-Jass Kristin
E.I. Du Pont de Nemours and Company
Gebreyesus Kagnew H
Rao Manjunath N
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