Host and vector for producing D-ribose

Details Host and vector for producing D-ribose Host and vector for producing D-ribose

1992-02-28

1994-01-25

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4353201, 536 232, C12N 121, C12N 1554, C12N 1574

Patent

active

052815315

ABSTRACT:
Disclosed are (1) a method of producing D-ribose which comprises cultivating a microorganism belonging to the genus Bacillus having D-ribose producing ability in a medium, the microorganism belonging to the genus Bacillus containing a DNA sequence participating in expression of a gluconate operon which is partly or wholly modified so as to highly express the gluconate operon in the microorganism belonging to the genus Bacillus, accumulating D-ribose, and collecting D-ribose thus obtained; (2) a novel microorganism belonging to the genus Bacillus having D-ribose producing ability transformed with DNA which contains a DNA sequence participating in expression of a gluconate operon which is partly or wholly modified so as to highly express the gluconate operon in the microorganism belonging to the genus Bacillus; (3) novel DNA in which a promoter of a gluconate operon of a microorganism belonging to the genus Bacillus is modified so as to highly express said gluconate operon in the microorganism belonging to the genus Bacillus; and (4) a novel vector into which DNA is introduced in which a promoter of a gluconate operon of a microorganism belonging to the genus Bacillus is modified so as to highly express the gluconate operon in the microorganism belonging to the genus Bacillus, whereby D-ribose can be produced in stable form in large amounts.

REFERENCES:
patent: 3970522 (1976-07-01), Sasajima et al.
Fujita et al. (1986), J. Biol. Chem. 261(29): 13744-13753.
Fujita et al. (1987), Proc. Nat. Acad. Sci USA 84: 4524-4528.
Lehninger (1982), Principles of Biochemistry, Worth Publishers Inc. (New York), pp. 456-457.
K. Sasajima et al., Carbohydrate Metabolism-Mutants of a Bacillus Species from Agricultural & Biological Chemistry, vol. 35, pp. 509-517 (1971).

Affiliated with

Also associated with

Rating

Host and vector for producing D-ribose does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Host and vector for producing D-ribose, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Host and vector for producing D-ribose will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-727269