Horseshoe crab hemocyte polypeptides, and preparation and DNA en

Details Horseshoe crab hemocyte polypeptides, and preparation and DNA en Horseshoe crab hemocyte polypeptides, and preparation and DNA en

1995-07-21

1999-01-19

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 530324, 530357, 530300, A61K 3817, C07K 14435

Patent

active

058613781

ABSTRACT:
The present invention relates to polypeptide having a primary structure of amino acid sequence shown by Sequence List Sequence No. 1 and DNA encoding for the polypeptide. The polypeptide is obtainable by following steps (1)-(3):

REFERENCES:
G. Allen. Sequencing of proteins and peptides. NewYork: North-Holland Publishing Co. pp. 43-62, 1981.
T. Shigenaga et al., "Separation of Large and Small Granules from Horseshoe Crab(Tachypleus Tridentatus ) Hemocytes and Characterization of Their Components" J. Biochem. 114:307-1316 (1993).
T. Murakami et al., "Direct Virus Inactivation of Tachyplesin I and Its Isopeptides from Horseshoe Crab Hemocytes" Chemotherapy 37:327-334 (1991).
M. Ohta et al., "Mechanisms of Antibacterial Action of Tachyplesins and Polyphemusins, A Group of Antimicrobial Peptides Isolated from Horseshoe Crab Hemocytes" Antimicrobial Agents and Chemotherapy 36:1460-1465 (1992).
T. Katsu et al., "Mode of Action of An Antimicrobial Peptide, Tachyplesin I, on Biomembranes" Biol. Pharm. Bull. 16(2):178-181 (1993).
N.G. Park et al., "Conformation of Tachyplesin I from Tachypleus Tridentatus When Interacting with Lipid Matrices" Biochemistry 31:12241-12247 (1992).
V.N. Korkryakov et al., "Protegrins: Leukocyte Antimicrobial Peptides that Combine Features of Corticostatic Defensins and Tachyplesins" FEBS 327(2):231-236 (1993).
K. Masuda et al., "Bactericidal Action of Tachyplesin I Against Oral Streptococci" Oral Microbiol. and Immunol. 9(2)77-80 (1994).
T. Saito et al., "A Novel Big Defensin Identified in Horseshoe Crab Hemocytes: Isolation, Amino Acid Sequence, and Antibacterial Activity" J. Biochem. 117:1131-1137 (1995).
T. Saito et al., "A Novel Type of Limulus Lectin-L6" J. Biol. Chem. 270(24):14493-14499 (1995).

Affiliated with

Also associated with

Rating

Horseshoe crab hemocyte polypeptides, and preparation and DNA en does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Horseshoe crab hemocyte polypeptides, and preparation and DNA en, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Horseshoe crab hemocyte polypeptides, and preparation and DNA en will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1246703