Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1994-05-20
1995-12-12
Wityshyn, Michael G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 54, 5361231, 53612312, A61K 31715, C08B 3700, C08B 3718
Patent
active
054749840
ABSTRACT:
This invention relates to a horseshoe crab amebocyte lysate factor G activation inhibitor comprising as an active ingredient a polyglycoside containing at least one poly-(1.fwdarw.3)-.beta.-D-glucoside structure portion consisting of 2 to 370 (1.fwdarw.3)-.beta.-D-glucoside structural units of the following formula ##STR1## which are continuously bound to one another. This inhibitor is useful for inhibiting the activation of factor G which may exist in horseshoe crab amebocyte lysate used in the Limulus test.
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FEBS Letters, vol. 129, No. 2, 1981 Jul. (North-Holland Biomedical Press), Morita, et al., "A New (1-3)-.beta.-D-Glucan Mediated Coagulation Pathway found in Limulus amebocytes", pp. 318-321.
Aketagawa Jun
Ohki Makoto
Shibata Yuko
Takahashi Shoji
Tamura Hiroshi
Seikagaku Kogyo Co. Ltd.
White Everett
Wityshyn Michael G.
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