Hormone preparation and method

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514171, 514843, 514899, 424449, A61K 3156

Patent

active

051089955

ABSTRACT:
This invention is concerned with a contraceptive formulation and a method of contraception which employs a combination of estrogen and progestin and wherein a short period of relatively dominant estrogenic activity alternates with a short period of relatively dominant progestagenic activity. The invention also concerns a hormonal replacement formulation and method for use in menopausal or castrate women which employs a similar combination of estrogen and progestin.

REFERENCES:
patent: 3409721 (1968-11-01), Applezweig
patent: 3502772 (1970-03-01), Ijzerman
patent: 3568828 (1971-03-01), Lerner
patent: 3758687 (1973-09-01), Ufer et al.
patent: 3795734 (1974-03-01), Rocheford
patent: 3822355 (1974-07-01), Kincl
patent: 3836651 (1974-09-01), Rudel et al.
patent: 3932635 (1976-01-01), Segre
patent: 3939264 (1976-02-01), Lachnit-Fixson
patent: 3942641 (1976-03-01), Segre
patent: 3957982 (1976-05-01), Lachnit-Fixson et al.
patent: 3969502 (1976-07-01), Lachnit-Fixson
patent: 4143136 (1979-03-01), De Jage et al.
patent: 4145416 (1979-03-01), Lachnit-Fixson et al.
patent: 4291028 (1981-09-01), Vorys
patent: 4292315 (1981-09-01), Vorys
patent: 4378356 (1983-03-01), De Jager
patent: 4390531 (1983-01-01), Edgren
patent: 4425339 (1984-01-01), Pitchford
patent: 4530839 (1985-07-01), Pasquale
patent: 4534468 (1985-08-01), Nuckols et al.
patent: 4544554 (1985-10-01), Pasquale
patent: 4605649 (1986-08-01), Liehr
patent: 4616006 (1986-10-01), Pasquale
patent: 4621079 (1986-11-01), Lachnit-Fixson et al.
patent: 4628051 (1986-12-01), Pasquale
patent: 4736849 (1988-04-01), Leonard et al.
patent: 4788062 (1988-11-01), Gale et al.
patent: 4826831 (1989-05-01), Plunkett et al.
patent: 4900734 (1990-02-01), Maxson et al.
patent: 4906169 (1990-03-01), Chein et al.
patent: 4921843 (1990-05-01), Pasquale
patent: 4962098 (1990-10-01), Boissonneault
patent: 4994449 (1991-02-01), Leonard
patent: 5023084 (1991-06-01), Chien et al.
Chemical Abstracts, vol. 96, No. 40915r.
Unlisted Drugs, vol. 38, No. 1, Jan. 1986, p. 2, Ref. O.
Chemical Abstracts, vol. 87, No. 16368h.
Rote Liste, 1987, Entry No. 75154 "Perkiursal".
Rote Liste, 1987, Entry No. 75156 "Sinovula".
Rote Liste, 1987, Entry No. 75157 "Synphasic".
Tseng et al., "Effects of Progestins on Estradiol Receptor Levels in Human Endometirum", J. Clin. Endocrinol. Metabl., vol. 41, pp. 402-407 (1975).
Bayard et al., "Cytoplasmic and Nuclear Estradiol and Progesterone Receptors in Human Endometrium", J. of Clin. Endocrinology and Metabolism, vol. 46, No. 4, pp. 635-648 (1978).
Kreitmann et al., "Estrogen and Progestin Regulation of the Progesterone Receptor Concentration in Human Endometrium", J. of Clin. Endocrinology and Metabolism, vol. 49, No. 6, pp. 926-929 (1979).
Walters et al., "Relationship between the Quantity of Progesterone Receptor and the Antagonism of Estrogen-Induced Uterotropic Response", Endocrinology, vol. 105, No. 2, pp. 382-386 (1979).
Kreitmann-Gimbal et al., "Patterns of Estrogen and Progesterone Receptors in Monkey Endometrium During the Normal Menstrual Cycle", Steroids, vol. 35, No. 4, pp. 471-479 (1980).
Alexandrova et al., "Oxytocin Receptors and Parturition in the Guinea Pig", Biology of Reproduction, vol. 22, pp. 1106-1111 (1980).
Katzenellenbogen, "Dynamics of Steroid Hormone Receptor Action", Ann. Rev. Physiol., vol. 42, pp. 17-35 (1980).
Whitehead et al., "Effects of Estrogens and Progestins on the Biochemistry and Morphology of the Postmenopausal Endometrium", New Engl. J. Med., vol. 305, No. 27, pp. 1599-1605 (1981).
Eckert et al., "Human Endometrial Cells in Primary Tissue Culture: Modulation of the Progesterone Receptor Level . . . ", J. of Clin. Endocrinology and Metabolism, vol. 52, No. 4, pp. 699-708 (1981).
West et al., "Progesterone-Mediated Suppression of Estradiol Receptors in Cynomolgus Macaque Cervix Endometrium and Oviduct . . . ", J. Steroid Biochem., vol. 22, No. 1, pp. 29-37, (1985).
Leavitt et al., "Rapid Recovery of Nuclear Estrogen Receptor and Oxytocin Receptor in the Ovine Uterus following Progesterone Withdrawal", J. Steroid Biochem., vol. 22, No. 6, pp. 687-691 (1985).
Neumannova et al., "Short-Term Effect of Tamoxifen, Medroxyprogesterone Acetate, and Their Combination on Receptor . . . ", Obstetrics & Gynecology, vol. 66, No. 5, pp. 695-700 (1985).
Jensen et al., "Continuous Oestrogen-Progestogen Treatment and Serum Lipoproteins in Postmenopausal Women", Brit. J. of Obstetrics and Gynaecology, vol. 94, pp. 130-135 (1987).
Rote Liste, 19-7, Ed. Cantor, Aulendorf, Wurttemberg, DE Nos. 75 157, 75 154, 75 156.
Unlisted Drugs, vol. 38, No. 1, Jan. 1986, p. 2, Chatham, N.J., U.S.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Hormone preparation and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hormone preparation and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hormone preparation and method will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1249526

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.