Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1987-03-23
1990-01-16
Phillips, Delbert R.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
C07R 710
Patent
active
048944360
ABSTRACT:
Microbially produced aprotinin and aprotinin homologs used for treating patients suffering from an excess release of pancreatic elastase, serum elastase or leukocyte elastase.
REFERENCES:
patent: 4595674 (1986-06-01), Tschesche et al.
Chem. Abstr. vol. 92 (1980) 142226b.
Chem. Abstr. vol. 89 (1978) 102675.
Chem. Abstr. vol. 88 (1978).
Chem. Abstr. vol. 106 (1987) 62156.
Chem. Abstr. vol. 104 (1986) 1703.
Wilcken-Bergmann et al, "A synthetic operon containing 14 bovon pancreatic trypsin inhibitor genes is expressed in E. coli", EMBO Journal, vol. 5, #12, pp. 3219-3225 (1986).
Anderson S., and Kingston, B. I. "Isolation of a genomic clone for bovine pancreatic trypsin inhibitor by using a unique-sequence synthetic DNA probe", Proc. Natl. Acad. Sci., USA, vol. 80, pp. 6838-6842, Nov. 1983 Biochemistry.
Jering et al, "Replacement of lysin by arginine, phenylalanine and tryptophan in the reactive site of the bovine trypsin-k allikrein inhibitor (kunitz) and charge of the inhibitory properties", Chemical Abstracts, vol. 84, p. 229, (1986).
Journal of Cellular Biochemistry, Suppl. 9B, 1985, Abstracts of 14th Annual Mettings, Mar. 9-Apr. 4, 1985, Marks, C. B. et al, "Expression and mutagenesis of bovine pancreatic tyrpsin inhibitor".
Auerswald Ernst-August
Bruns Wolfgang
Kotick Michael
Reinhardt Gerd
Schnabel Eugen
Bayer Aktiengesellschaft
Phillips Delbert R.
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