Homogeneous preparations of IL-28 and IL-29

Details Homogeneous preparations of IL-28 and IL-29 Homogeneous preparations of IL-28 and IL-29

2006-10-16

2009-02-24

Bunner, Bridget E. (Department: 1647)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Lymphokines, e.g., interferons, interlukins, etc.

C424S085200, C435S320100, C435S471000, C435S069520, C435S810000, C435S975000, C536S023500

Reexamination Certificate

active

07495078

ABSTRACT:
Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.

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