Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Reexamination Certificate
2007-01-02
2007-01-02
O'Hara, Eileen (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
C435S069520, C435S320100, C435S471000, C424S085200, C536S023500
Reexamination Certificate
active
10914772
ABSTRACT:
Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
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Brady Lowell J.
Bukowski Thomas R.
Chan Chung
Dong Dennis L.
Klucher Kevin M.
Hamud Fozia
O'Hara Eileen
Walsh Brian J.
ZymoGenetics Inc.
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