Homogeneous luminescence energy transfer bioassay

Details Homogeneous luminescence energy transfer bioassay Homogeneous luminescence energy transfer bioassay

2005-06-09

2009-08-04

Cook, Lisa V (Department: 1641)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S006120, C435S007100, C435S007920, C436S501000, C436S518000

Reexamination Certificate

active

07569355

ABSTRACT:
A homogeneous bioassay including a first group labelled with an energy donor and a second group labelled with an energy acceptor, where the donor is a luminescent lanthanide label capable of up-converting a lower-energy excitation to a higher-energy emission, where the acceptor is either a luminescent or a non-luminescent label, and where the increase or decrease, respectively, in energy transfer from the donor to the acceptor resulting from shortening or lengthening of the distance between the labels is measured. The assay is performed in a biological fluid which absorbs radiation in the wavelength range 300 to 600 nm, the measurement is carried out at a wavelength >570 nm, and the donor label, which is excitable at wavelength longer than its emission wavelength, is excited in the wavelength window in which the biological fluid does not essentially absorb the excitation radiation.

REFERENCES:
patent: 5891656 (1999-04-01), Zarling et al.
patent: 5998146 (1999-12-01), Latva et al.
patent: 6159686 (2000-12-01), Kardos et al.
patent: 6444476 (2002-09-01), Morgan
patent: 2002/0119498 (2002-08-01), Joung et al.
patent: WO 89/11868 (1989-12-01), None
patent: WO 96/01297 (1996-01-01), None
patent: WO 98/15830 (1998-04-01), None
patent: WO 02/44725 (2002-06-01), None
patent: WO 02/44725 (2002-06-01), None
patent: WO 03/074630 (2003-09-01), None
Niedbala et al. (Analytical Biochemistry, vol. 293, 2001, pp. 22-30).
Lee et al. (Cytometry, vol. 21, 1995, pp. 120-128).
Soukka et al., “Novel Homogeneous Assay Technology Based on Up-Converting Nanophosphors,” (Univ. Of Turku Apr. 13, 2005).
Soukka et al., “Novel Homogeneous Assay Technology Based On Up-converting Nanophosphors,” (Univ. Of Turku Apr. 13, 2005).

Affiliated with

Also associated with

Rating

Homogeneous luminescence energy transfer bioassay does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Homogeneous luminescence energy transfer bioassay, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Homogeneous luminescence energy transfer bioassay will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4081808