Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is particulate and the particles are of...
Reexamination Certificate
2007-04-10
2009-02-17
Le, Long V (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is particulate and the particles are of...
C435S007100, C435S007920, C435S007930, C435S007940, C436S518000, C436S164000, C436S172000
Reexamination Certificate
active
07491553
ABSTRACT:
A homogeneous immunoassay method and system for quantitative determination of total immunoglobulin E and specific antibody levels to a plurality of allergens, in which a relatively small sampling of blood is required. The method utilizes relatively small microparticles in aqueous suspension. The immunoassay procedure is an immunometric sandwich procedure preferably utilizing biotin-streptavidin signal amplification techniques and R-phycoerytherin fluorescent labels.
REFERENCES:
patent: 4279617 (1981-07-01), Masson et al.
patent: 4459360 (1984-07-01), Marinkovich
patent: 4520110 (1985-05-01), Stryer et al.
patent: 4743541 (1988-05-01), Higgins et al.
patent: 5082768 (1992-01-01), Burd et al.
patent: 5478926 (1995-12-01), Nishimura et al.
patent: 5494830 (1996-02-01), Hubscher
patent: 5512659 (1996-04-01), Ullman et al.
patent: 5972630 (1999-10-01), Cromer et al.
patent: 5981180 (1999-11-01), Chandler et al.
patent: 6054303 (2000-04-01), Davalian et al.
patent: 6087188 (2000-07-01), Johansen et al.
patent: 6159748 (2000-12-01), Hechinger
patent: 6245513 (2001-06-01), Lane et al.
patent: 6264619 (2001-07-01), Ferguson
patent: 6268222 (2001-07-01), Chandler et al.
patent: 6449562 (2002-09-01), Chandler et al.
patent: 2002/0004199 (2002-01-01), Hechinger
patent: 2002/0055176 (2002-05-01), Ray
patent: WO 97/14028 (1997-04-01), None
Diamandis et al., Immunoassay, Academic Press, Chapter 11, The Avidin-Biotin System, pp. 237-267, 1996.
Wild et al., The Immunoassay Handbook, p. 54, 1994.
Anonymous; “FluoroTable: Common fluorophores”; 2001, http://web.archive.org/web/20011203181756/http://info.med.yale.edu/genetics/ward/tavi/FISHdyes2.html, 6 pages.
Fulton, R. Jerrold et al.; “Advanced multiplexed analysis with the FlowMetrix™ system”; 1997,Clinical Chemistry, vol. 43, No. 9, pp. 1749-1756.
Hlavacek, William S. et al.; “Quantifying Aggregation of IgE-FcεRI by Multivalent Antigen”; 1999,Biophysical Journal, vol. 76, pp. 2421-2431.
Carpenter, A.B. “Enzyme-linked immunoassays,” Chapter 2In Manual of Clinical Laboratory Immunology, 4th Edition, 1992. N.R. Rose et al. eds. American Society for Microbiology, Washington D.C., pp. 2-6.
Haugland, R.P. and Bhalgat, M.K. “Preparation of avidin conjugates,” Chapter 18In Immunochemical Protocols, 2nd Edition, 1998. J.D. Pound ed. Humana Press Inc., Totowa, N.J., pp. 185-196.
Johansson, S.G.O. and Yman, L. “In vitro assays for immunoglobin E,”Clinical Reviews in Allergy, 1988, pp. 93-139, vol. 6.
Nakamura, A.B. and Robbins, B.A. “Fluorescence immunoassays,” Chapter 3In Manual of Clinical Laboratory Immunology, 4th Edition, 1992. N.R. Rose et al. eds. American Society for Microbiology, Washington, D.C., pp. 7-15.
Wild et al.The Immunoassay Handbook, Signal Generation and Detection Systems. M stockton press. New York 1994, pp. 63-82, see pp. 76-77.
Brown Christopher R.
Murai James T.
Boyer Brian S.
Counts Gary W
ImmuneTech, Inc.
Le Long V
TIPS Group
LandOfFree
Homogeneous immunoassays for multiple allergens does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Homogeneous immunoassays for multiple allergens, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Homogeneous immunoassays for multiple allergens will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4076018