Homogeneous immunoassays employing double antibody conjugates co

Details Homogeneous immunoassays employing double antibody conjugates co Homogeneous immunoassays employing double antibody conjugates co

1984-03-29

1987-04-28

Marantz, Sidney

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 12, 435 21, 435 28, 436501, 436518, 436524, 436528, 436540, 436800, G01N 3353, G01N 33566, G01N 33543, G01N 33551

Patent

active

046614443

ABSTRACT:
Homogeneous immunoassays employing double ligand binding conjugates comprising an anti-idiotype binding partner. The anti-idiotype binding partner competes with ligand for an insolubilized ligand specific binding partner. Inhibition of binding of the conjugate to the insolubilized binding partner due to ligand binding permits the second binding partner in the conjugate to bind with insolubilized label means. Thus, detection of label is inversely related to the presence of ligand in the sample.

REFERENCES:
patent: 4433059 (1984-02-01), Chang et al.

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