Homogeneous immunoassay using covalent hybrid antibodies

Details Homogeneous immunoassay using covalent hybrid antibodies Homogeneous immunoassay using covalent hybrid antibodies

1982-05-05

1984-05-01

Marantz, Sidney

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

436537, 436547, 436817, G01N 3354, G01N 3358

Patent

active

044462336

ABSTRACT:
An immunoassay for analytes such as antigens or haptens, which utilizes covalent hybrid antibodies to modulate the activity of indicators. The hybrid antibody has binding sites for the analyte and the indicator. Final activity of the indicator is proportional to analyte concentration.

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V. Raso et al., Cancer Research, 41, 2073-2078, (Jun. 1981).
A. Nisonoff et al., Archives of Biochemistry and Biophysics, 93(1), 460-462, (Apr. 1961).
Hammerling et al., J. Exp. Med., 128, 1461, (1968).
Hong et al., J. Biol. Chem., 240, 3883, (1965).

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