Homobidental, trifunctional linkers used in immunologically acti

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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A61K 3940, A61K 3944

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active

056018240

ABSTRACT:
Compound of the general formula ##STR1## wherein R is an ester-activating group, m and n are identical or different and 0-6, p =0, 2-4, and q and s=1, p=0 if s=0 and p=2-4 if s=1. The compound is novel and suitable for the reproducible coupling of immunological substances at a high yield.

REFERENCES:
patent: 5082930 (1992-01-01), Nicolotti et al.
patent: 5083930 (1992-01-01), Barron
patent: 5091542 (1992-02-01), Ahlem et al.
patent: 5168057 (1992-12-01), Oh et al.
patent: 5244785 (1993-09-01), Loor et al.
Derwent Abstract, 85-226374 of JP 60146154, cited under 85-226374 (1985).

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