Homo-prostaglandin derivatives as ocular hypotensives

Details Homo-prostaglandin derivatives as ocular hypotensives Homo-prostaglandin derivatives as ocular hypotensives

1992-03-17

1993-11-16

Killos, Paul J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

554214, 560122, A01N 3708, C01C 302

Patent

active

052624374

ABSTRACT:
The invention relates to homo-prostaglandin derivatives. More particularly, the present invention concerns 1a-homo derivatives of naturally occurring and synthetic prostaglandins, the corresponding bis- and trishomo-prostaglandin compounds, and their 1-esters and salts. The homo-prostaglandin compounds of the present invention are potent ocular hypotensives, and are particularly suitable for the management of glaucoma.

REFERENCES:
patent: 4013695 (1977-03-01), Lin
patent: 4024167 (1977-05-01), Bundy et al.
patent: 4051160 (1977-09-01), Bundy et al.
patent: 4105682 (1978-08-01), Bundy
patent: 4122100 (1978-10-01), Yankee
CA98 (7):49788a 1982.
CA95 (5):36216a 1981.
CA95 (1):1055v 1981.
CA 87(19):151771z 1977.
CA 98(25):215362d 1983.
CA 106(11):79289q 1986.
Cornette, James C. and Kirton, Kenneth, "Radioimmunoassay of Prostaglandins and their Metabolites", Mar. 4-5, 1976, 1977, Proceedings of the International Symposium on Prostaglandins in Hematology, Philadelphia, pp. 69-85, New York.
Tobias, L. D. et al., "The Biosynthesis of 1a,1b-DIHOMO-PGE.sub.2 * and 1a,1b-DIHOMO-PGF.sub.20c from 7, 10, 13, 16-Docosatetraenoic Acid by an Acetone-Pentane Powder of Sheep Vesicular Gland Microsomes", Sep. 1975, pp. 443-469, Prostaglandins, vol. 10, No. 3.

Affiliated with

Also associated with

Rating

Homo-prostaglandin derivatives as ocular hypotensives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Homo-prostaglandin derivatives as ocular hypotensives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Homo-prostaglandin derivatives as ocular hypotensives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-22935