Homekit for determining attention deficit hyperactivity...

Surgery – Diagnostic testing – Temperature detection

Reexamination Certificate

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C600S300000

Reexamination Certificate

active

06482165

ABSTRACT:

FIELD OF THE INVENTION
This invention relates in general to a technique for diagnosing Attention Deficit Hyperactivity Disorder (ADHD) and more particularly to a home kit technique for measuring an individual's peripheral temperature to determine values indicative of ADHD.
BACKGROUND OF THE INVENTION
ADHD is the most common neurobehavioral disorder of childhood as well as among the most prevalent health conditions affecting school-aged children. Between 4% and 12% of school age children (several millions) are affected. $3 billion is spent annually on behalf of students with ADHD. Moreover, in the general population, 9.2% of males and 2.9% of females are found to have behavior consistent with ADHD. Upwards of 10 million adults may be affected.
ADHD is a difficult disorder to diagnose. The core symptoms of ADHD in children include inattention, hyperactivity, and impulsivity. ADHD children may experience significant functional problems, such as school difficulties, academic underachievement, poor relationships with family and peers, and low self-esteem. Adults with ADHD often have a history of losing jobs, impulsive actions, substance abuse, and broken marriages. ADHD often goes undiagnosed if not caught at an early age and affects many adults who may not be aware of the condition. ADHD has many look-alike causes (family situations, motivations) and co-morbid conditions (depression, anxiety, learning disabilities).
Diagnosis of ADHD involves a process of elimination using written and verbal tests. However, there is no one objective, independent valid test for ADHD. Various objective techniques have been proposed but have not yet attained acceptance. These include:
1. The eye problem called convergence insufficiency was found to be three times more common in children with ADHD than in other children by University of California, San Diego researchers.
2. Infrared tracking to measure difficult-to-detect movements of children during attention tests combined with functional MRI imaging of the brain were used by psychiatrists at McLean Hospital in Belmont, Mass. to diagnose ADHD in a small group of children (
Nature Medicine
, Vol. 6, No. 4, April 2000, Pages 470-473).
3. Techniques based on EEG biofeedback for the diagnoses and treatment of ADHD are described by Lubar (
Biofeedback and Self-Regulation
, Vol. 16, No. 3, 1991, Pages 201-225).
4. U.S. Pat. No. 5,913,310, issued Jun. 22, 1999, inventor Brown, discloses a video game for the diagnosis and treatment of ADHD.
5. U.S. Pat. No. 5,377,100, issued Dec. 27, 1994, inventors Pope et al., discloses a method of using a video game coupled with brain wave detection to treat patients with ADHD.
6. Dr. Albert Rizzo of the Integrated Media Systems Center of the University of Southern California has used Virtual Reality techniques for the detection and treatment of ADHD.
Although skin temperature spectral characteristics have been shown to indicate stress-related changes of peripheral vasomotor activity in normal subjects, there has been no disclosure of use of variations in skin-temperature response to assist in diagnosing ADHD. (See:
Biofeedback and Self-Regulation
, Vol. 20, No. 4, 1995).
As discussed above, the primary method for diagnosing ADD is the use of a bank of written and verbal tests designed to assess criteria established by American Medical Association (AMA) as described in the Diagnostic and Statistics manual-IV (DSM-IV) and administered by the school psychologist or other licensed practitioner. In some cases those individuals who meet DSM-IV criteria for ADHD diagnosis are prescribed a drug such as Ritalin. Behavioral observations of the patient while on Ritalin are conducted to assess the imact of prescribed medication. U.S. patent application (Ser. No. 09/597,610) describes an apparatus and method of determining whether an individual has Attention Deficit Disorder. In none of the prior art is there disclosed a method for screening for ADHD at home using a home kit.
There is thus a need for a simple, inexpensive, and reliable technique for determining whether an individual has Attention Deficit Hyperactivity Disorder (ADHD) in the home.
SUMMARY OF THE INVENTION
According to the present invention, there is provided a solution to the problems and fulfillment of the needs discussed above.
According to a feature of the present invention, there is provided a kit for determining whether an individual has Attention Deficit Hyperactivity Disorder (ADHD) comprising:
a device for sampling the peripheral skin temperature of a human subject during a predetermined time interval when the subject is in an inactive state; and
an analyzer for analyzing the sampled peripheral skin temperature data for a pre-selected parameter, to determine whether said pre-selected parameter has a value indicative of ADHD.
ADVANTAGEOUS EFFECT OF THE INVENTION
The invention has the following advantages.
1. A device and technique for diagnosing ADHD is provided which is simple, inexpensive and reliable and usable in the home in the form of a kit.


REFERENCES:
patent: 4920973 (1990-05-01), Tanaka et al.
patent: 5365939 (1994-11-01), Ochs
patent: 5377100 (1994-12-01), Pope et al.
patent: 5725472 (1998-03-01), Weathers
patent: 5913310 (1999-06-01), Brown
patent: 5947908 (1999-09-01), Morris
patent: 5995857 (1999-11-01), Toomim et al.
patent: 6117075 (2000-09-01), Barnea
patent: 6238354 (2001-05-01), Alvarez
Nature Magazine, Apr. 2000, vol. 6, No. 4, pp 470-473, Functional deficits in basal ganglia of children with attention-deficit/hyperactivity disorder shown with functional magnetic resonance imaging relaxometry, by Martin H. Treicher, Carl M. Anderson, Ann Polcari, Carol A. Glod, Luis C. Maas and Perry F. Renshaw.
Biofeedback and Self-Regulation, vol. 16, No. 3, 1991, Research Recognition Award paper, Disclosure on the Development of EEG Diagnostics and Biofeedback for Attention-Deficit/Hyperactivity Disorders, by Joel F. Lubar, University of Tennessee.
Biofeedback and Self-Regulation, vol. 20, No. 4, 1995, Spectral Characteristics of Skin Temperature Indicate Peripheral Stress-Response, by Vladimir Shusterman and Ofer Barnea, Tel Aviv University.
U.S. patent application Ser. No. 09/597,610, filed on Jul. 20, 2000, by Richard N. Blazey, Peter A. Parks, David L. Patton.

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