Hollow fiber membrane type oxygenator and method for manufacturi

Chemical apparatus and process disinfecting – deodorizing – preser – Blood treating device for transfusible blood – Oxygenator

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261122, 261DIG28, 128DIG3, 55 16, 55158, 21032162, 21032181, 2103219, 21050022, 21050023, A61M 114

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049236792

ABSTRACT:
A hollow fiber membrane type oxygenator is provided wherein a bundle of a plurality of hollow porous fibers presenting gas exchange membranes axially extends through a housing to define a first flow path for oxygen, a pair of partitions support the opposed open ends of the hollow fibers to isolate the open ends from the first flow path to define a second flow path through the fiber cavities for blood, and the micropores in the hollow fibers are filled with a silicone compound, for exmaple, a RTV silicone rubber or a blend thereof with a silicone oil while the hollow fibers on their side wall are substantially free of a layer of the silicone compound. The oxygenator is manufactured by prefabricating an oxygenator module of the above-mentioned construction, impregnating the hollow fibers with a solution of the silicone compound, and passing a cleaning liquid to remove excessive silicone compound, thereby filling only the micropores with the silicone compound.

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Akamatsu, Kiyoshi et al., Chemical Abstracts, Jun. 27, 1979, vol. 91, p. 43, No. 141845v.
S. Sifniades et al., Hydrometallurgy, Jan. 15, 1981, "Recovery of Uranium from Phosphoric Acid by Means of Supported Liquid Membranes", pp. 202-212.
Rompps Chemisches Worterbuch, "Silicone" pp. 804-806 (1969) and partial English language translation.
Murphy et al., "Laboratory and Clinical Experience with a Microporous Membrane Oxygenator", Trans. Am. Soc. Artil. Organs, vol. XX, 1974, pp. 278-283.

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