Hollow fiber immobilization with chopped microporous hollow fibe

Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...

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435240242, 435243, 4352521, 4352541, 4352551, 4352401, 4352891, 4352931, 4352974, 4352991, C12N 1104, C12N 500, C12N 100, C12N 120, C12N 114, C12N 116, C12M 300, C12M 304, C12M 104

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055102573

ABSTRACT:
Most of the problems of prior art techniques for growing cells in hollow fiber devices can be avoided by growing the cells in short lengths (e.g., two inches (5.0 cm.) or less) of microporous hollow fibers. The fibers are prepared by chopping commercial lengths of hollow fibers into small pieces, preferably two inches (5 cm.) or smaller. Such chopped hollow fibers or bundles of hollow fibers are then added to a suitable medium for growth of cells and the medium is incubated. Very high cell densities have been observed in the chopped fibers.

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