Hollow fiber cell propagation system and method

Details Hollow fiber cell propagation system and method Hollow fiber cell propagation system and method

1990-02-15

1992-06-30

Warden, Robert J.

Chemistry: molecular biology and microbiology

Condition responsive control process

4352401, 435240242, 435284, 435289, 435291, 435807, 422 8204, 204409, C12N 500, C12M 304, C12M 136

Patent

active

051262380

ABSTRACT:
A unique hollow fiber bioreactor system and method for the propagation of cells and the production of various cell propagation products is described. The system and method include the use of a flow block holder which allows a dissolved oxygen probe to be calibrated at the same pressure as the media in the bioreactor system.

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patent: 4720462 (1988-01-01), Rosenson
patent: 4764471 (1988-08-01), Ripka
patent: 4889812 (1989-12-01), Guinn et al.
patent: 4999298 (1991-03-01), Wolfe et al.
Schweitzer, Handbook of Separation Techniques for Chemical Engineers, 2nd Ed., McGraw Hill, 1988 pp. 2-21, 22.
Seaver, S., Editor, Commercial Production of Monoclonal Antibodies--A Guide for Scale-Up, Marcel Dekker, Inc., N.Y., 1987, pp. 119-138.

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