Hog cholera virus vaccine and diagnostic

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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4241841, 530350, 530395, 536 231, A61K 39187, A61K 3900, C07K 100, C07K 1400

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active

059253606

ABSTRACT:
The present invention is concerned with a hog cholera virus vaccine comprising a polypeptide characteristic of hog cholera virus. Vector vaccines capable to express a nucleic acid sequence encoding such a polypeptide also form part of the present invention. Said polypeptide and nucleic acid sequence can also be used for the detection of hog cholera virus infection.

REFERENCES:
R.J.M. Moorman et al., "Hog Cholera Virus: Identification and Characterization of the viral RNA and the Virus-Specific RNA Synthesized in Infected Swine Kidney Cells", Virus Research, vol. 11, No. 4, 1988, pp. 281-291, 1988.
M.S. Collett et al., "Recent Advances in PestVirus Research", The Journal of Genearl Virology, vol. 70, No. 2, Feb. 1989, pp. 253-266.
G. Meyers et al., "Molecular Cloning and Nucleotide Sequence of the Genome of Hog Cholera Virus", Virology, vol. 171, No. 2, pp. 555-567, Academic Press, 1989.
Moorman et al., Virus Research, 11, pp. 281-291 (1988).
Collett et al., Virology, 165, pp. 191-199 (1988).
Collett et al., Virology, 165, pp. 200-208 (1988).
Declaration of R.J.M. Moorman, and enclosures 1-4, re: oral presentation on Dec. 8, 1988.
Thesis of G. Wensvoort, entitled Epitopes on Structural Proteins of Hog Cholera (Swine Fever) Virus, dated Mar. 9, 1989, publicly available Mar. 14, 1989.
Collett et al., J. Gen. Virol., 70, pp. 253-266 (1989).
Dalsgaard et al, Acta Vet. Scand., 17, pp. 465-474 (1976).
Renard et al., DNA, 4, pp. 429-438 (1985).
Rumenapf et al., Virology, 171, pp. 18-27 (1989).
Meyers et al., Virology, 171, pp. 555-567 (Aug. 1989).
Geysen et al., J. Immun. Methods, 102, pp. 259-274 (1987).

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