HMGN2 peptides and related molecules that selectively home...

Details HMGN2 peptides and related molecules that selectively home... HMGN2 peptides and related molecules that selectively home...

2008-10-20

2011-11-01

Yu, Misook (Department: 1642)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

C530S350000, C435S007250

Reexamination Certificate

active

08048983

ABSTRACT:
The present invention provides a conjugate which contains a therapeutic moiety linked to a homing molecule that selectively homes to tumor blood vessels and tumor cells and that specifically binds the receptor bound by peptide KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK (SEQ ID NO: 9). Methods of directing a conjugate of the invention to tumor blood vessels and tumor cells and of using a conjugate to treat cancer also are provided.

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