HMG-COA reductase inhibitors

Details HMG-COA reductase inhibitors HMG-COA reductase inhibitors

1987-06-29

1988-11-01

Milestone, Norma S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549292, 560119, 514824, A61K 31365, C07D30930

Patent

active

047820845

ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) or (II): ##STR1## and pharmaceutically acceptable salts thereof the compounds of the formula (II) in which R.sup.1 is hydrogen are disclosed.

REFERENCES:
patent: 4231938 (1980-11-01), Monaghan et al.

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