Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-04-24
2010-02-09
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S026000
Reexamination Certificate
active
07659281
ABSTRACT:
Compounds are provided of the following structure are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol, and treating hyperlipidemia and dyslipidemia, hypercholesterolemia, hypertriglyceridemia and atherosclerosiswherein variables A and B are defined herein.
REFERENCES:
patent: 4906624 (1990-03-01), Chucholowski et al.
patent: 4925852 (1990-05-01), Kesseler et al.
patent: 5006530 (1991-04-01), Angerbauer et al.
patent: 5169857 (1992-12-01), Angerbauer et al.
patent: 5177080 (1993-01-01), Angerbauer et al.
patent: 5686433 (1997-11-01), Robl
patent: 5753675 (1998-05-01), Wattanasin
patent: 6620821 (2003-09-01), Robl
patent: 6627636 (2003-09-01), Robl
patent: 6812345 (2004-11-01), Robl et al.
patent: 6875867 (2005-04-01), Brodfuehrer et al.
patent: 0306929 (1989-03-01), None
patent: 0307342 (1989-03-01), None
patent: 0325129 (1989-07-01), None
patent: 0325130 (1989-07-01), None
patent: 0491226 (1992-06-01), None
patent: 0444533 (1997-06-01), None
patent: 0818197 (1998-01-01), None
“Fibric Acid”, http://medical-dictionary.thefreedictionary.com/fibric+acid, accessed Dec. 30, 2008.
Sietsema et al. Expert Opinion on Investigational Drugs, 1994, 3(12), 1255-76.
J. Robl et al., “Phosphorous Containing Inhibitors of HMG-CoA Reductase. 2.1Synthesis and Biological Activities of a Series of Substituted Pyridines Containing A Hydroxyphosphinyl Moiety2”, J. Med. Chem., 34, 2804-2815, 1991.
Carini David J.
He Chunhong
Markwalder Jay A.
Robl Jeffrey A.
Seitz Steven P.
Bristol--Myers Squibb Company
Jarrell Noble
Rodney Burton
Wilson James O
LandOfFree
HMG-CoA reductase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with HMG-CoA reductase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and HMG-CoA reductase inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4173027