HMG CoA-reductase inhibitors

Details HMG CoA-reductase inhibitors HMG CoA-reductase inhibitors

2006-07-18

2006-07-18

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S517000

Reexamination Certificate

active

07078430

ABSTRACT:
The invention relates to particular hydroxyl and protected hydroxyl derivatives of compounds known to be useful as HMG CoA-reductase inhibitors. In particular, herein are provided hydroxyl and protected hydroxyl compounds of Formula Iand their corresponding lactones.

REFERENCES:
patent: 4681893 (1987-07-01), Roth
patent: 5273995 (1993-12-01), Roth
patent: 5298627 (1994-03-01), Butler et al.
patent: 5385929 (1995-01-01), Bjorge et al.
Lea and McTavish, “Atorvastatin. A Review of its Pharmacology and Theraputic Potential in the Management of Hyperlipidaemias”,Drugs, 53(5):828-847 (1997).
Kubo and Strott, “Differential Activity of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase in Zones of the Adrenal Cortex”,Endocrinology; 120(1):214-221 (1987).
Heller and Gould, “Solubilization and Partial Purification of Hepatic 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase”,Biochemical and Biophysical Research Communications, 50(3):859-865 (1973).
C.B. Reese, “Chapter 3—Protection of Alcoholic Hydroxyl Groups and Glycol Systems”Protective Groups in Organic Chemistry, Edited by J.F.W. McOmie, Plenum Press, New York, NY (1973).

Affiliated with

Also associated with

Rating

HMG CoA-reductase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with HMG CoA-reductase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and HMG CoA-reductase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3588645