Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1989-12-05
1991-02-26
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
562469, 562429, 562430, 562431, 562435, 562437, 562438, 562455, 562452, 514559, 514561, 514562, 514563, 514564, 514570, 514824, A61K 3119, A61K 3120, C07C 6230, C07C 6204
Patent
active
049962345
ABSTRACT:
Disclosed are novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula ##STR1## and the corresponding ring-opened hydroxy acids derived therefrom and pharmaceutically acceptable salts thereof.
Pharmaceutical compositions containing said compounds and method of inhibiting the biosynthesis of cholesterol therewith are also disclosed.
REFERENCES:
patent: 4282155 (1981-08-01), Smith et al.
patent: 4308378 (1981-12-01), Stokker
patent: 4503072 (1985-03-01), Hoffman et al.
patent: 4567289 (1986-01-01), Willard et al.
patent: 4611067 (1986-09-01), Volank et al.
patent: 4622338 (1986-11-01), Baran et al.
patent: 4668699 (1987-05-01), Hoffman et al.
patent: 4681893 (1987-07-01), Roth
patent: 4772626 (1981-09-01), Smith et al.
Neuenschwander Kent W.
Regan John R.
Balogh Imre (Jim)
Nicholson James A.
Raymond Richard L.
Rhone-Poulenc Rorer Pharmaceuticals Inc.
Russell Mark W.
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