HMG-CoA reductase inhibitor metabolites

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514824, 514529, 514559, 514574, 560119, 549292, A61K 3135, C07D30930

Patent

active

051128578

ABSTRACT:
This invention relates to compounds of formulae I and II ##STR1## which are metabolites of tetrahydrosimvastatin and 5-hydroxy-tetrahydrosimvastatin and which are HMG-CoA reductase inhibitors.

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patent: 4963538 (1990-10-01), Duggan et al.
Terahara et al., "MB-530B derivatives and their pharmaceutical compositions" CA 99:70288t (1983).

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