HMG-COA reductase inhibitor metabolites

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549292, A61K 31365

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active

053859324

ABSTRACT:
This invention relates to compounds of formulae I and II ##STR1## which are metabolites of tetrahydrosimvastatin and 5-hydroxy-tetrahydrosimvastatin and which are HMG--CoA reductase inhibitors.

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Terahara et al. "MB 530B Derivatives and their Pharmaceutical Compositions" CA 99: 70288t (1983).

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