HLA typing

Details HLA typing HLA typing

1991-05-10

1993-10-26

Saunders, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

422 56, 435 724, 435962, 435970, 435975, 436518, 436526, 436530, 436531, 436536, 436548, 436809, 436824, 436825, G01N 33543, G01N 33577

Patent

active

052565432

ABSTRACT:
Physiological samples are typed for HLA-B27 by contacting the sample with an antibody which binds to HLA-B7 and is not cross-reactive between HLA-B7 and B27, separating the sample from any complexes which are formed, and then testing the sample for the presence of HLA-B27 with an antibody which is cross-reactive for HLA-B7 and B27 in a STAT test. Particularly, an enzyme conjugate is used which binds to a membrane allowing for the detection of any HLA-B27 bound to the membrane.

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