Chemistry: analytical and immunological testing – Biospecific ligand binding assay – Utilizing isolate of tissue or organ as binding agent
Patent
1983-04-19
1985-01-08
Padgett, Benjamin R.
Chemistry: analytical and immunological testing
Biospecific ligand binding assay
Utilizing isolate of tissue or organ as binding agent
436504, 436804, 436811, 436823, 436815, 435 4, 435 29, 435 35, 4351722, 435174, 435240, 435948, 935101, 935110, G01N 3350, C12N 1500
Patent
active
044927606
ABSTRACT:
An assay for HLA D phenotype wherein antigen-pulsed monocytes are contacted with antigen-specific T lymphocytes or T cell hybridomas and the extent of selective binding between the pulsed monocytes and the T lymphocytes or T cell hybridomas determines HLA D phenotype of the monocyte. The assay is particularly useful for quickly typing donor tissue prior to transplantation.
REFERENCES:
patent: 4124701 (1978-11-01), Bach et al.
patent: 4265873 (1981-05-01), Sheehy et al.
patent: 4294802 (1981-10-01), Johansson
patent: 4314026 (1982-02-01), Descamps-Latscha
patent: 4318886 (1982-03-01), Kawahara et al.
Kearns, R. J. et al., Federation Proceedings; FASEB, vol. 39, (3), p. 355, Abstract 449, (1980).
Skidmore, B. J. et al., Federation Proceedings; FASEB, vol. 39, (3), p. 936, Abstract 3517, (1980).
DeFreitas, E. et al., Federation Proceedings; FASEB, vol. 39, (3), p. 944, Abstract 3554, (1980).
Rosenthal, A. S. et al., Immunology 80, eds. Fougereau, M. & Dauesset, J., p. 458, Academic Press, London, (1980).
DeFreitas et al., (1982), Current Topics in Microbiology and Immunology, 100: 191-201.
Foundation Marcell Merieux, Abstract Book, Sixth International Conference on Tetanus, (Lycon, France, Dec. 3-5, 1981).
Maizel et al., (1982), Proceeding of the National Academy of Sciences USA, 79: 5998-6002.
Mayer et al., (1982), Journal of Experimental Medicine, 156: 1860-1865.
Butler et al., (1983), Journal of Experimental Medicine, 157: 60-68.
Lakow et al., (1983), Journal of Immunology, 130: 169-172.
Foung et al., (1982), Proceedings of the National Academy of Sciences USA, 79: 7484-7488.
Green et al., (1982), Journal of Immunology, 129: 1986-1992.
Kobayashi et al., (1982), Journal of Immunology, 128, 2714-2718.
Okata et al., (1981), Proceedings of the National Academy of Sciences USA, 78: 7717-7721.
Irigoyen et al., (1981), Journal of Experimental Medicine, 154: 1827-1837.
Grillot-Courvaline et al., (1981), Nature, 292: 844-845.
DeFreitas et al., (1982), Proceedings of the National Academy of Sciences USA, 79: 6646-6650.
Fox, Chemical & Engineering News, pp. 15-17, (Jan. 1, 1979).
Moskowitz M.
Padgett Benjamin R.
The Wistar Institute of Anatomy and Biology
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