HKABY60: polynucleotide encoding a helix-loop-helix ubiquitous k

Details HKABY60: polynucleotide encoding a helix-loop-helix ubiquitous k HKABY60: polynucleotide encoding a helix-loop-helix ubiquitous k

1998-07-29

2000-07-11

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Insect cell, per se

4352541, 435363, 4352523, 435410, 536 232, C12N 1554, C12N 1574, C12N 1582, C12N 1585

Patent

active

060871695

ABSTRACT:
HKABY60 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HKABY60 polypeptides and polynucleotides in the design of protocols for the treatment of cancer, inflammatory disorders, immune disorders and viral diseases, among others, and diagnostic assays for such conditions.

REFERENCES:
patent: 5843721 (1998-12-01), Rothe et al.
patent: 5851812 (1998-12-01), Goeddel et al.
Regnier et al., "Identification and Characterization of an I.kappa.B Kinase" Cell. vol. 90 (2), pp. 373-383 (1997).
Woronicz et al., "I.kappa.B Kinase-.beta.: NF-.kappa.B Activation and Complex Formation with I.kappa.B Kinase-.alpha.and NIK.", Science, vol. 278, pp. 866-869 (1997).
HGS EST# 1660004.

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